Mixing And Blending, Powder Flow, Food Texture, Bulk Mixing, and Food Processing news and information
PRODUCTS
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Scale AAV production with peace of mind. Extend transfection complex formation time by up to 3 hours, reduce complex volume by >50%, and maintain high titers and full capsids.
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Through a science-led approach and extensive experience in product development, our team can support you with aseptic and terminally sterilized small volume liquids, as well as lyophilized and spray dried powders for parenteral, ocular and pulmonary delivery.
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The eSWIR 640CSX+MMT represents a cutting-edge advancement in extended shortwave infrared (eSWIR) imaging, offering up to 2.2 µm spectral response with integrated multi-mode tracking (MMT).
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The leader in digitizing validation
Setting the digital validation standard for 20 years, ValGenesis VLMS is used by 30 of the top 50 global life sciences companies.
The gold standard of standardization
Strengthen your compliance stance and lower the cost of quality with enforced standardization and absolute data integrity.
Knowledge integrity to data integrity
Gain total peace of mind with a single source of validation truth with documentation aligned to ALCOA+ standards.
One platform, boundless scale
Start small or start global. VLMS scales effortlessly to support new systems, new sites, new products, new languages, and new validation processes.
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Anritsu's aerosol checkweigher is engineered for accurate weighing of aerosol cans in pharmaceutical applications. It features a star wheel mechanism that feeds cans onto the weigh table at a constant speed and with uniform spacing. This design, combined with a high precision electromagnetic weigh cell, ensures a throughput of up to 150 cans per minute, with a weighing accuracy of ± 10 mg. The checkweigher has a compact footprint, integrating within the same frame a reject mechanism and confirmation function, ensuring that only correctly weighed products pass through. Underweight and overweight cans are automatically directed into two separate bins located beneath the weigh table. The system is compliant with federal regulation 21 CFR Part 11 for the integrity of electronic records and signatures, with features such as password authentication, audit trail of operation data, and encryption/decryption of exported data.
WHITE PAPERS AND CASE STUDIES
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Saving Dollars And Crushing Odors: How SulFeLox® Outperformed Calcium Nitrate In Tackling H2S
Faced with increased chemical prices, a large facility in Tennessee wanted to trial SulFeLox as a potential alternative to their BIOXIDE program.
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Escondido, CA Uses Cityworks And Esri's ArcGIS® For Its Asset Management System
Read about water utility managers who took advantage of an offer from Trimble to do a pilot program for creating a ‘system of action’ that focuses on leveraging their investment in Esri’s ArcGIS® and water sensor data, location intelligence, and analytics tools.
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Designing Extrusions With Additional Processing
A medical device company worked to redesign a critical component and consolidate extrusion and secondary operations. The project was successfully completed in six months.
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Optimizing Local Affiliate PV Operations
Discover how a global biopharmaceutical company partnered with PharmaLex to implement a streamlined, standardized model for international ICSR processing, compliance, and cross-functional collaboration.
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ProPharma Supports A Contract Manufacturer's Form 483 Response
Learn how a small contract manufacturer navigated a complex FDA 483 Observation notice and implemented effective remediation strategies that addressed multiple system-wide concerns.
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Helium Leak Detection On Glass Cartridge Containers
Helium leak detection offers unmatched sensitivity for verifying glass cartridge seal integrity. Learn how this advanced method outperforms traditional tests and provides confidence in packaging.
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Rapid And Robust Preclinical And Clinical Development Of CAR T-Cell Therapies
Streamline CAR T-cell therapy development with integrated support for asset identification, IND submission, early-phase studies, and advanced real-time tracking solutions.
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CRO Uses CRIO eSource To Double Monitoring Productivity
Examine the transformative impact of eSource technology on monitoring productivity during a global Phase 3 trial conducted by a Contract Research Organization (CRO) amid the COVID-19 pandemic.
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Bridging The Gap During Organizational Restructuring For Continuity
Navigating workforce turnover and restructuring can threaten project timelines. Discover how leveraging an experienced on-site team can ensure long-term continuity.
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Delivering Specialist Neurology Support
Explore a strategic approach to a Parkinson’s disease trial that leveraged a global infrastructure and multilingual workforce to provide seamless operational and clinical support.
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Trial Rescue: Leadership Approach To Propel Clinical Development
Learn how Halloran's assistance was able to improve a rare disease biotechnology company’s development and operations, communication workflow, and avoid the delay of a gene therapy trial.
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Medable's Japanese Clinical Trial Exceeds FPI Date And eCOA Adherence
A top-10 global pharma company aimed to address eCOA adherence and patient enrollment challenges faced by clinical trial sites in Japan. Explore an initiative to enhance the patient and site experience.
NEWS
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PNE Group Receives Permits For Three New Wind Farms In Germany7/8/2025
In the second quarter of 2025, the PNE Group received the necessary permits for the construction and operation of three onshore wind farms in the German states of Brandenburg, Hesse, and North Rhine-Westphalia.
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Drawing Inspiration From Ancient Chemical Reactions3/20/2025
To help find solutions to the planet’s climate crisis, MIT Associate Professor Daniel Suess is looking to Earth’s ancient past.
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Silo Pharma Expands Intellectual Property Portfolio With Patent Application For Exclusively Licensed Alzheimer's Drug4/28/2025
Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced the filing of a patent application with the U.S. Patent and Trademark Office (USPTO) focused on the neurology drug SPC-14, an intranasal compound for the treatment of Alzheimer’s disease (AD) exclusively licensed to Silo Pharma from Columbia University.
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PulpFixin Announces Strategic Distribution Partnership With Wildcat Laboratory Solutions To Expand Sustainable Lab Products Across The UK And EU4/14/2025
PulpFixin, an innovator of sustainable laboratory products, announced today a new distribution partnership with Wildcat Laboratory Solutions a leading provider of lab equipment and solutions across the United Kingdom and European Union.
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Quantum Biopharma Announces Signing Of An Agreement With A Global Pharmaceutical Contract Research Organization To Prepare An IND (Investigational New Drug) Application Package For Lucid-21-302 (Lucid-MS), A First-In-Class Treatment For Multiple Sclerosis5/20/2025
Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91) (“Quantum BioPharma” or the “Company”), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions, today announces that it has signed an agreement with a global pharmaceutical contract research organization to prepare an IND (Investigational New Drug) application package for Lucid-21-302 (Lucid-MS) with the US FDA.
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Mixing and Blending
Mixing and blending are terms that have specific meaning in the food industry. Most food processing experts use the word mixing to describe the process of combining wet and dry materials.
Blending is the term used to describe the process of combining only dry ingredients. The term blending is generally reserved for powders, flakes and granules of varying bulk densities and particle size that require gently blending and minimal contact with blender blades.
Agitation is often used synonymously with the term mixing. However, in food processing, agitation is used to ensure the mixing process to get a homogenous mix is completed faster.
Many industries require the mixing of free-flowing powders. The art of mixing involves different dilution geometries (a geometry is a way of combining unequal amounts of fine powders to ensure an equal distribution).
The geometric mix used depends on the size distribution, shape, particle density, composition and internal structures. Other properties include flow ability, bulk density, mixture quality, dustiness and properties of segregation.
Industrial mixers are used to do the blending and mixing. The shape and hardness of the materials being mixed affects the horsepower required to run the mixer. The type of mixer used in a production line varies depending on the materials that need to be mixed or blended. Paddle mixers are often the best choice for production line mixing because they are easy to clean, have less surface area, and have a minimal number of parts.
Mixing and blending is generally a sub-process within an overall process cycle so when placing a mixer it is important to consider how it integrates into the whole system. That includes impacts to both upstream and downstream product handling.