Mixing And Blending, Powder Flow, Food Texture, Bulk Mixing, and Food Processing news and information Mixing And Blending, Powder Flow, Food Texture, Bulk Mixing, and Food Processing news and information

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    Plastic Syringe Assembly

    We cover the pre-assembly of a plastic syringe with cannula, as well as the final assembly of multi-component syringes (4-8 or 8-12 components).

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    4 - 40 GHz Wideband Gain Block: AMM-9862PSM

    The AMM-9862PSM is a compact, wideband gain block amplifier designed for high-performance RF applications.

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    Compaction Simulation / Emulation

    Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.

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    USP<1062> Tablet Compression Characterization

    Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.

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    How iMednet Addresses Key Industry Challenges

    In today’s complex clinical research landscape, sponsors and CROs face numerous challenges that can impact study timelines, costs, and data quality. The iMednet platform offers innovative solutions to address these critical issues.

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Mixing and Blending
Mixing and blending are terms that have specific meaning in the food industry.  Most food processing experts use the word mixing to describe the process of combining wet and dry materials.
Blending is the term used to describe the process of combining only dry ingredients.  The term blending is generally reserved for powders, flakes and granules of varying bulk densities and particle size that require gently blending and minimal contact with blender blades.
Agitation is often used synonymously with the term mixing. However, in food processing, agitation is used to ensure the mixing process to get a homogenous mix is completed faster.
Many industries require the mixing of free-flowing powders. The art of mixing involves different dilution geometries (a geometry is a way of combining unequal amounts of fine powders to ensure an equal distribution).
The geometric mix used depends on the size distribution, shape, particle density, composition and internal structures.  Other properties include flow ability, bulk density, mixture quality, dustiness and properties of segregation.
Industrial mixers are used to do the blending and mixing.  The shape and hardness of the materials being mixed affects the horsepower required to run the mixer.  The type of mixer used in a production line varies depending on the materials that need to be mixed or blended. Paddle mixers are often the best choice for production line mixing because they are easy to clean, have less surface area, and have a minimal number of parts.
Mixing and blending is generally a sub-process within an overall process cycle so when placing a mixer it is important to consider how it integrates into the whole system. That includes impacts to both upstream and downstream product handling.