Mixing And Blending, Powder Flow, Food Texture, Bulk Mixing, and Food Processing news and information
PRODUCTS
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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Setting a New Benchmark for Ease of Operation
The NP-255 is a robust tablet press that was built to meet even the most demanding needs of the mid-sized tableting industry. The press has features and options designed to increase production, improve tablet quality, reduce waste, and set a new benchmark for ease of operation. Designed, engineered, and manufactured in the USA, this unique machine has a maximum production speed of 192,000 tablets per hour.
With a hardened steel die table, a gravity feeder that is interchangeable with a two-paddle forced feeder, and our industry-leading intuitive Natoli AIM™ ProPluscontrol system, the NP-255 is the new standard for value in the mid-sized tableting industry.
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Accelerate your clinical trials with an expansive network of over 2,000 high-quality, trusted clinical trial sites across Australia, New Zealand, United States and Canada.
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The LightIR thermal imaging zoom lenses are lightweight, compact, and high-performance, designed for a range of reduced SWaP applications, including UAVs, aircraft vision systems, drones, and more.
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Gain access to Culture bioreactors when you need rapid overflow experimental capacity.
Benefits
Progress studies faster
Run overflow projects and conduct parallel experiments with Culture to reduce time and alleviate bottlenecks.
Stay agile in your capacity planning
Scale your workload at Culture according to your current needs. Respond rapidly to surging demands.
Eliminate your capital equipment spend
Leverage Culture’s facility quickly to avoid building out lab space, spending capital on equipment, and hiring specialized staff.
WHITE PAPERS AND CASE STUDIES
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Enhancing Treatment Capacity With miGRATE™ Technology At Verrado WRF
Due to rapid population growth in its service area, Verrado Water Reclamation Facility (WRF) in Verrado, Arizona faced a challenge. Its existing treatment capacity of 1.54 millions of gallons per day (MGD) had become insufficient to meet the rising demand and comply with both Total Suspended Solids (TSS) and Total Nitrogen (TN) permits.
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Controlling Biofouling In Governador José Richa Power Plant, Brazil
Read about an extensive study that was carried out to evaluate the ability of the HOD UV system to control biofouling in the Governador José Richa Power Plant.
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Accelerating A Complex Molecule From CLD To cGMP In 12 Months
Learn how to mitigate technical risk, implement parallel process development, and design custom purification strategies for highly sensitive novel modalities to accelerate to cGMP material.
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Improving Pre-Clinical Study Efficiency With mRNA-LNP Technology
Uncover how Repair Biotechnologies, in collaboration with Vernal Biosciences, helped to pave the way for the next generation of breakthrough treatments for cholesterol and aging-related diseases.
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Why A Leading Manufacturing Partner Chose NeoTOP Packaging Machines
Learn how a leading CDMO partnered with Körber to quickly deploy a high-speed packaging solution to meet tight production deadlines in the face of a global pandemic.
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Flatiron Prospective Evidence Generation
Explore prospective evidence generation and pragmatic approaches that can help you address staffing challenges and the issue of complexity that is driving up the failure rate of clinical studies.
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MilliporeSigma's 97-Day Implementation Success Story
Read how MilliporeSigma transformed validation processes with a digital validation system to achieve compliance in just 97 days, as well as learn key takeaways from their swift transition.
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CAR-T And Laminar Flow Glovebox Isolators
A request was made for a containment system that would protect operators during lentivirus transfer, as well as provide a controlled environment for IL-2 charging of media, bead addition, and blood bag spiking.
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EHR-To-EDC Success In A Complex, Adaptive Platform Trial
I-SPY 2, one of the longest-running adaptive platform trials in oncology, is revolutionizing breast cancer research through a dynamic, data-driven approach to evaluating novel therapies.
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Safety Assessment Of Intravitreal Implants In Dutch Belted Rabbits
Address unique anatomical challenges to deliver reliable, IND-enabling data for innovative therapies by relying on our expertise to design and execute your complex ocular safety study.
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Leverage Apps To Reduce Line Changeover Time From 14 Days To 3
A global biopharma leader modernized its complex equipment changeover process using an innovative platform to achieve faster execution, fewer errors, and greater visibility through digitized, validatable SOPs.
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Integrated Water Intelligence: Digital Water Metering And Digital Twin Technology
Integrating digital metering with digital twins transforms raw data into actionable network intelligence. This unified approach enables precise hydraulic simulations and proactive maintenance, helping utilities eliminate operational guesswork while improving water quality and system efficiency.
NEWS
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Anritsu Unveils New Software-Based Solution For 5G IoT Chipset And Device Development Tests2/28/2025
Anritsu Corporation is proud to introduce the Virtual Signalling Tester NR Software MX844030PC, a software-based test simulator for developing 5G IoT chipsets and devices. The solution supports 5G IoT test by using a new simulator that operates in a virtual environment on a PC using advanced architecture, as well as a Software Defined Radio (SDR) that implements most conventional radio functions in software.
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Silo Pharma Expands Intellectual Property Portfolio With Patent Application For Exclusively Licensed Alzheimer's Drug4/28/2025
Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced the filing of a patent application with the U.S. Patent and Trademark Office (USPTO) focused on the neurology drug SPC-14, an intranasal compound for the treatment of Alzheimer’s disease (AD) exclusively licensed to Silo Pharma from Columbia University.
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GD Energy Products' Y-Shaped Drilling Module Now Rated For 10,000 PSI8/18/2025
GD Energy Products (GDEP), the leading total solutions provider for the frac, drilling and well servicing pumps market, has announced its patented Y-Shaped Drilling Module is now rated for operating pressures up to 10,000 psi.
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New Land Grant Research Detects Dicamba Damage From The Sky7/9/2025
Drones can now detect subtle soybean canopy damage from dicamba at one ten-thousandth of the herbicide’s label rate — simulating vapor drift — eight days after application.
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Meatable And TruMeat Collaborate To Accelerate Cost-Effective Cultivated Meat Production4/30/2025
Meatable, the leader in cultivated meat technology, and TruMeat, specializing in the contract manufacturing of cultivated meat at commercial scale, have formed a strategic collaboration to advance the global commercialization of cultivated meat.
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Mixing and Blending
Mixing and blending are terms that have specific meaning in the food industry. Most food processing experts use the word mixing to describe the process of combining wet and dry materials.
Blending is the term used to describe the process of combining only dry ingredients. The term blending is generally reserved for powders, flakes and granules of varying bulk densities and particle size that require gently blending and minimal contact with blender blades.
Agitation is often used synonymously with the term mixing. However, in food processing, agitation is used to ensure the mixing process to get a homogenous mix is completed faster.
Many industries require the mixing of free-flowing powders. The art of mixing involves different dilution geometries (a geometry is a way of combining unequal amounts of fine powders to ensure an equal distribution).
The geometric mix used depends on the size distribution, shape, particle density, composition and internal structures. Other properties include flow ability, bulk density, mixture quality, dustiness and properties of segregation.
Industrial mixers are used to do the blending and mixing. The shape and hardness of the materials being mixed affects the horsepower required to run the mixer. The type of mixer used in a production line varies depending on the materials that need to be mixed or blended. Paddle mixers are often the best choice for production line mixing because they are easy to clean, have less surface area, and have a minimal number of parts.
Mixing and blending is generally a sub-process within an overall process cycle so when placing a mixer it is important to consider how it integrates into the whole system. That includes impacts to both upstream and downstream product handling.