WHITE PAPERS AND CASE STUDIES

• Optimizing Recruitment For Urgently Needed Vaccine

  Uncover how Citeline Connect helped a late-stage biotech sponsor expedite enrollment of a diverse population of eligible patients impacted by monkeypox for a large Phase 1 and Phase 2 trial of a next-generation vaccine.

• Modelling TPDs Utilizing Computational And Medicinal Chemistry Approaches

  Through a carefully executed strategy, see how we identified novel degrader molecules with the right physicochemical properties to achieve robust degradation of the target Protein of Interest (POI).

• 82 Million Gallons In. Zero PFAS Out.

  Ion exchange resin is a reliable, high-capacity solution for municipal PFAS treatment, demonstrating zero detectable PFAS after processing 82 million gallons of water. The technology offers a significantly smaller footprint and superior volumetric capacity compared to GAC. Read the full case study to review performance data and strategic impacts.

• What The Hidden Springs Pilot Case Study Reveals About Cutting-Edge Water Treatment

  A seven-month pilot study shows how ozone treatment reduced hydrogen sulfide and TOC at the Hidden Springs Water Treatment Facility, improving water quality and validating a scalable alternative.

• Enabling Simpler, Quieter, And More Precise Wearables Utilizing Disruptive Pump Technology

  Disc pumps enable quieter, smaller, and more precise wearable medical devices, improving patient comfort, measurement accuracy, and system reliability for innovative healthcare solutions.

• Optimizing Chronic Cough Phase 3 Trials With Point-Of-Need Eye Assessments

  Collaboration was key for Company W to overcome challenges with an FDA-mandated ocular substudy, including limited resources for ocular assessments and logistical difficulties

• Rural North Texas Community Cuts Non-Revenue Water By 42% With Pipeline Leak Detection Technology

  Discover how a city solved its non-revenue water challenge by rapidly pinpointing three hard-to-find leaks in 13 miles of aging pipeline using a free-swimming acoustic tool.

• Large-Scale Exosome Production Stirred-Tank Bioreactors

  Discover how engineered exosomes, displaying tumor-homing peptides, offer a promising tool for targeted cytotoxic drug delivery, produced efficiently with a bioreactor for critical research.

• Aseptic Expertise And Delivery Of Services

  A pharmaceutical services company sought expert intervention after a routine requalification of their aseptic simulation process revealed a contaminated unit, halting commercial production for two months.

• Development Strategies For Adenovirus-Based Gene Therapies

  Scaling up viral vector production can be challenging, and ensuring consistent titers and activity requires careful optimization and technical expertise.

• SL-RAT At Little Rock Water Reclamation Authority

  Little Rock looked to enhance their sophisticated cleaning program and reduce sanitary sewer overflow count by implementing new technologies.

• Development To Large-Scale cGMP Production

  For manufacturers working with a dry powder medium (DPM), early consultation with a supplier can increase the likelihood of success. Uncover a two-phase scale-up strategy for the production of DPM.