Download | April 12, 2007

Automated Diafiltration (Washing) of Protein Solutions: BioProcessing System Maintains Safe TFF Conditions

Source: SciLog, Inc.
The SciPro Smart BioProcessing System™ automates constant volume diafiltration, i.e. removal of undesirable electrolyte (dissolved salts) from dilute protein solutions. In this procedure, the process solution containing the protein is re-circulated through a tangential flow filtration (TFF) device. The undesirable electrolyte is collected as permeate while the protein is left behind as retentate.

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