QC Methods That Make A Difference: The Challenge Of Measuring Powder Flowability

By Bob McGregor, Brookfield Engineering

What does it take to put effective qualification tests into QC for powder processors? Pharmaceutical products that satisfy not only manufacturability criteria, but also provide a high level of consumer satisfaction, undergo a battery of physical property tests before being introduced into production. Using affordable instrumentation to perform these QC tests is an essential part of today’s successful business.

Corporations willingly invest in devices used to test physical properties which measure flowability of powders. Proper flow behavior is essential to keep the production line running smoothly without interruption. Powders comprised of multiple components require a throughput process which preserves this “mixed” condition. The possibility of desegregation of component particles is a potential pitfall that accompanies “core flow” behavior, a “first in – last out” flow pattern that is more the norm than the exception.