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Technical Paper: Issues In Microfeeding
As anyone who works with bulk solid materials knows, accurately and reliably controlling the flow rate of material at normal process rates can be challenging. Add to the challenge the need to control the flow of some minor ingredients in the process in micro-regions as low as 20g/ hr. Further compound the challenge by requiring a level of precision that permits only a scant few percent sample-tosample variation. This is the challenge of microfeeding.
The development of microfeeding technology emerged primarily as a result of the recent decade's shift toward Process Automation Technology (PAT) as sanctioned by the FDA. This initiative has hastened application of continuous processing techniques in the pharmaceutical industry. Moving to a continuous process necessitates the elimination of manual feeding of minor ingredients and creates a real need for microfeeding technology.
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